Publications

Coutinho, L. L., Femino, E. L., Gonzalez, A. L., Moffat, R. L., Heinz, W. F., Cheng, R. Y. S., Lockett, S. J., Rangel, M. C., Ridnour, L. A. & Wink, D. A. NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer. Int. J. Mol. Sci. 25, 6103 (2024). https://doi.org/10.3390/ijms25116103

Degenhardt, M. F. S., Degenhardt, H. F., Bhandari, Y. R., Lee, Y.-T., Ding, J., Yu, P., Heinz, W. F., Stagno, J. R., Schwieters, C. D., Watts, N. R., Wingfield, P. T., Rein, A., Zhang, J. & Wang, Y.-X. Determining structures of RNA conformers using AFM and deep neural networks. Nature 1–10 (2024). https://doi.org/10.1038/s41586-024-07559-x

Kundu, M., Greer, Y. E., Lobanov, A., Ridnour, L., Donahue, R. N., Ng, Y., Ratnayake, S., Voeller, D., Weltz, S., Chen, Q., Lockett, S. J., Cam, M., Meerzaman, D., Wink, D. A., Weigert, R. & Lipkowitz, S. TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers. bioRxiv (2024).07.19.604341. https://doi.org/10.1101/2024.07.19.604341

Osei-Amponsa, V., Chandravanshi, M., Lu, X., Magidson, V., Das, S., Andresson, T., Dyba, M., Sabbasani, V. R., Swenson, R. E., Fromont, C., Shrestha, B., Zhao, Y., Clapp, M. E., Chari, R. & Walters, K. J. hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50. Mol. Cell 84, 522-537.e8 (2024). https://doi.org/10.1016/j.molcel.2023.11.035

Osei-Amponsa, V., Magidson, V. & Walters, K. J. Protocol for cytoskeleton staining of the semi-adherent multiple myeloma cell line RPMI 8226 by immunofluorescence. STAR Protoc. 5, 103060 (2024). https://doi.org/10.1016/j.xpro.2024.103060

Reddy, T., Puri, A., Guzman-Rojas, L., Thomas, C., Qian, W., Zhou, J., Zhao, H., Mahboubi, B., Oo, A., Cho, Y.-J., Kim, B., Thaiparambil, J., Rosato, R., Martinez, K. O., Chervo, M. F., Ayerbe, C., Giese, N., Wink, D., Lockett, S., Wong, S., Chang, J., Krishnamurthy, S., Yam, C., Moulder, S., Piwnica-Worms, H., Meric-Bernstam, F. & Chang, J. NOS inhibition sensitizes metaplastic breast cancer to PI3K inhibition and taxane therapy via c-JUN repression. 15, 10737 (2024). https://doi.org/10.1038/s41467-024-54651-x

Ridnour, L. A., Cheng, R. Y. S., Kedei, N., Somasundaram, V., Bhattacharyya, D. D., Basudhar, D., Wink, A. L., Walke, A. J., Kim, C., Heinz, W. F., Edmondson, E. F., Butcher, D. O., Warner, A. C., Dorsey, T. H., Pore, M., Kinders, R. J., Lipkowitz, S., Bryant, R. J., Rittscher, J., Wong, S. T. C., Hewitt, S. M., Chang, J. C., Shalaby, A., Callagy, G. M., Glynn, S. A., Ambs, S., Anderson, S. K., McVicar, D. W., Lockett, S. J. & Wink, D. A. Adjuvant COX inhibition augments STING signaling and cytolytic T cell infiltration in irradiated 4T1 tumors. JCI Insight 9, e165356 (2024). https://doi.org/10.1172/jci.insight.165356

Ridnour, L. A., Heinz, W. F., Cheng, R. Y., Wink, A. L., Kedei, N., Pore, M., Imtiaz, F., Femino, E. L., Gonzalez, A. L., Coutinho, L. L., Moffat, R. L., Butcher, D., Edmondson, E. F., Li, X., Rangel, M. C., Kinders, R. J., Rittscher, J., Lipkowitz, S., Wong, S. T. C., Anderson, S. K., McVicar, D. W., Glynn, S. A., Billiar, T. R., Chang, J. C., Hewitt, S. M., Ambs, S., Lockett, S. J. & Wink, D. A. Tumor NOS2 and COX2 Spatial Juxtaposition with CD8+ T Cells Promote Metastatic and Cancer Stem Cell Niches that Lead to Poor Outcome in ER- Breast Cancer. Cancer Res. Commun. 4, 2766–2782 (2024). https://doi.org/10.1158/2767-9764.crc-24-0235

Sarkar, S., Anderson, C. F., Xie, Y., Lockett, S. J. & Schneider, J. P. Aliphatic and Aromatic Dialdehydes as Chemical Cross-Linkers for Self-Assembled Peptide Gels. Chemistry of Materials 36, 10216–10226 (2024). https://doi.org/10.1021/acs.chemmater.4c01955

Ridnour LA, Cheng RYS, Heinz WF, Pore M, Gonzalez AL, Femino EL, Moffat R, Wink AL, Imtiaz F, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Wong STC, Lipkowitz S, Glynn S, Vitek MP, McVicar DW, Li X, Anderson SK, Paolocci N, Hewitt SM, Ambs S, Billiar TR, Chang JC, Lockett SJ, Wink DA. Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients. bioRxiv [Preprint]. (2023).12.21.572867. https://doi.org/10.1101/2023.12.21.572867 PMID: 38187660

Ridnour LA, Heinz WF, Cheng RY, Wink AL, Kedei N, Pore M, Imtiaz F, Femino EL, Gonzalez AL, Coutinho L, Butcher D, Edmondson EF, Rangel MC, Kinders RJ, Lipkowitz S, Wong ST, Anderson SK, McVicar DW, Li X, Glynn SA, Billiar TR, Chang JC, Hewitt SM, Ambs S, Lockett SJ, Wink DA  NOS2 and COX2 Provide Key Spatial Targets that Determine Outcome in ER- Breast Cancer. bioRxiv [Preprint]. (2023).12.21.572859. https://doi.org/10.1101/2023.12.21.572859

Ahn, J. I., Zhang, L., Ravishankar, H., Fan, L., Kirsch, K., Zeng, Y., Meng, L., Park, J.-E., Yun, H.-Y., Ghirlando, R., Ma, B., Ball, D., Ku, B., Nussinov, R., Schmit, J. D., Heinz, W. F., Kim, S. J., Karpova, T., Wang, Y.-X. & Lee, K. S. Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells. Commun. Biol. 6, 712 (2023). https://doi.org/10.1038/s42003-023-05067-8

Cheng, R. Y. S., Ridnour, L. A., Wink, A. L., Gonzalez, A. L., Femino, E. L., Rittscher, H., Somasundaram, V., Heinz, W. F., Coutinho, L., Rangel, M. C., Edmondson, E. F., Butcher, D., Kinders, R. J., Li, X., Wong, S. T. C., Mcvicar, D. W., Anderson, S. K., Pore, M. & Hewitt, S. M. Interferon-gamma is quintessential for NOS2 and COX2 expression in ER – breast tumors that lead to poor outcome. Cell Death and Disease 12 (2023). https://doi.org/10.1038/s41419-023-05834-9

Moissoglu, K., Lockett, S. J. & Mili, S. Cell Migration in Three Dimensions. Methods Mol. Biol. (Clifton, NJ) 2608, 263–280 (2023). https://doi.org/10.1007/978-1-0716-2887-4_16

Wang, Y.-X., Degenhardt, M., Degenhardt, H., Bhandari, Y., Lee, Y.-T., Ding, J., Heinz, W., Stagno, J., Schwieters, C. & Zhang, J. Determining structures of individual RNA conformers using atomic force microscopy images and deep neural networks. Res. Sq. rs.3.rs-2798658 (2023). https://doi.org/10.21203/rs.3.rs-2798658/v1

Salotti, J., Asif, N., Basu, S., Das, A., Yang, M., Karim, B., Saylor, K., Martin, N., Scheiblin, D. A., Misra, S., Luke, B. T., Andresson, T., Lockett, S., Tessarollo, L. & Johnson, P. F. 3’UTR-directed, kinase proximal mRNA decay inhibits C/EBPβ phosphorylation/activation to suppress senescence in tumor cells. bioRxiv [Preprint] (2022).486281. https://doi.org/10.1101/2022.03.29.486281

Somasundaram, V., Ridnour, L. A., Cheng, R. Y., Walke, A. J., Kedei, N., Bhattacharyya, D. D., Wink, A. L., Edmondson, E. F., Butcher, D., Warner, A. C., Dorsey, T. H., Scheiblin, D. A., Heinz, W., Bryant, R. J., Kinders, R. J., Lipkowitz, S., Wong, S. T., Pore, M., Hewitt, S. M., McVicar, D.W., Anderson, S.K., Chang, J., Glynn, S. S., Ambs, S., Locket, S. J., Wink, D. A. (2022). Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density. Redox Biology, 58(November), 102529. https://doi.org/10.1016/j.redox.2022.102529

Fernandez-de Céspedes, M. V, Hoffman, H. K., Carter, H., Simons, L. M., Naing, L., Ablan, S. D., Scheiblin, D. A., Hultquist, J. F., van Engelenburg, S. B., & Freed, E. O. (2022). Rab11-FIP1C is Dispensable for HIV-1 Replication in Primary CD4(+) T Cells, but its Role is Cell Type Dependent in Immortalized Human T-Cell Lines. Journal of Virology, 96(23), e0087622. https://doi.org/10.1128/jvi.00876-22

Basu, S., Luke, B. T., Karim, B., Martin, N., Lockett, S., Das, S., Andresson, T., Saylor, K., Kozlov, S., Bassel, L., Esposito, D., & Johnson, P. F. (2022). CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of KRAS mutant cancers. BioRxiv, 2022.04.05.487175. https://doi.org/10.1101/2022.04.05.487175

Lee, H. K., Conrad, C. E., Magidson, V., Heinz, W. F., Pauly, G., Yu, P., Ramakrishnan, S., Stagno, J. R., & Wang, Y. (2022). Developing methods to study conformational changes in RNA crystals using a photocaged ligand. Frontiers in Molecular Biosciences, August, 1–13. https://doi.org/10.3389/fmolb.2022.964595

delas Peñas, K. E., Haeusler, R., Feng, S., Magidson, V., Dmitrieva, M., Wink, D., Lockett, S., Kinders, R., & Rittscher, J. (2022). Profiling DNA Damage in 3D Histology Samples. In Y. Huo, B. A. Millis, Y. Zhou, X. Wang, A. P. Harrison, & Z. Xu (Eds.), Medical Optical Imaging and Virtual Microscopy Image Analysis (pp. 84–93). Springer Nature Switzerland. https://doi.org/10.1007/978-3-031-16961-8_9

Smith CE, Tsai Y.C., Liang Y.H., Khago D., Mariano J., Li J., Tarasov S.G., Gergel E., Tsai B., Villaneuva M., Clapp M.E., Magidson V., Chari R., Byrd R.A., Ji X., Weissman A.M. (2021). A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation. PLoS Biol. Dec 8;19(12). https://doi.org/10.1371/journal.pbio.3001474

Trofka, A., Huang, B.-L., Zhu, J., Heinz, W. F., Magidson, V., Shibata, Y., Shi, Y.-B., Tarchini, B., Stadler, H. S., Kabangu, M., Al Haj Baddar, N. W., Voss, S. R., & Mackem, S. (2021). Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates. Current Biology, 1–12. https://doi.org/10.1016/j.cub.2021.09.010

Ramakrishnan, S., Stagno, J. R., Heinz, W. F., Zuo, X., Yu, P., & Wang, Y.-X. (2021). The mechanism driving a solid–solid phase transition in a biomacromolecular crystal. IUCrJ, 8(4), 655–664.https://doi.org/10.1107/s2052252521004826

Ramakrishnan, S., Stagno, J. R., Magidson, V., Heinz, W. F., & Wang, Y.-X. (2021). Dependence of phase transition uniformity on crystal sizes characterized using birefringence. Structural Dynamics, 8(3), 034301. https://doi.org/10.1063/4.0000098

McGinity, C. L., Palmieri, E. M., Somasundaram, V., Bhattacharyya, D. D., Ridnour, L. A., Cheng, R. Y. S., Ryan, A. E., Glynn, S. A., Thomas, D. D., Miranda, K. M., Anderson, S. K., Lockett, S. J., McVicar, D. W., & Wink, D. A. (2021). Nitric oxide modulates metabolic processes in the tumor immune microenvironment. International Journal of Molecular Sciences, 22(13). https://doi.org/10.3390/ijms22137068

Ramakrishnan, S., Stagno, J. R., Magidson, V., Heinz, W. F., & Wang, Y.-X. (2021). A combined approach to characterize ligand-induced solid–solid phase transitions in biomacromolecular crystals. Journal of Applied Crystallography, 54(3), 787–796. https://doi.org/10.1107/s1600576721003137

Sjoberg, H. T., Philippou, Y., Magnussen, A. L., Tullis, I. D. C., Bridges, E., Chatrian, A., Lefebvre, J., Tam, K. H., Murphy, E. A., Rittscher, J., Preise, D., Agemy, L., Yechezkel, T., Smart, S. C., Kinchesh, P., Gilchrist, S., Allen, D. P., Scheiblin, D. A., Lockett, S. J., Wink, D.A., Lamb, A.D., Mills, I.G., Harris, A., Muschel, R.J., Vojnovic, B., Scherz, A., Hamdy, F.C. Bryant, R. J. (2021). Tumour irradiation combined with vascular-targeted photodynamic therapy enhances antitumour effects in pre-clinical prostate cancer. British Journal of Cancer, 125(4), 534–546. https://doi.org/10.1038/s41416-021-01450-6

Gilmore, A. C., Flaherty, S. J., Somasundaram, V., Scheiblin, D. A., Lockett, S. J., Wink, D. A., & Heinz, W. F. (2021). An in vitro tumorigenesis model based on live-cell- generated oxygen and nutrient gradients. Communications Biology, 4(477), 1–13. https://doi.org/10.1038/s42003-021-01954-0

Ramakrishnan, S., Stagno, J. R., Conrad, C. E., Ding, J., Yu, P., Bhandari, Y. R., Lee, Y., Pauly, G., Yefanov, O., Wiedorn, M. O., Knoska, J., Oberthür, D., White, T. A., Barty, A., Mariani, V., Li, C., Brehm, W., Heinz, W. F., Magidson, V., Wang, Y.-X. (2021). Synchronous RNA conformational changes trigger ordered phase transitions in crystals. Nature Communications. https://doi.org/10.1038/s41467-021-21838-5

Rausch, J. W., Heinz, W. F., Payea, M. J., Sherpa, C., Gorospe, M., & Le Grice, S. F. J. (2021). Characterizing and circumventing sequence restrictions for synthesis of circular RNA in vitro. Nucleic Acids Research. https://doi.org/10.1093/nar/gkaa1256

Renda, F., Magidson, V., Tikhonenko, I., Fisher, R., Miles, C., Mogilner, A., & Khodjakov, A. Effects of malleable kinetochore morphology on measurements of intrakinetochore tension. Open Biology, 10(7), 200101. (2020).  https://doi.org/10.1098/rsob.200101

Biswas, K., Lipton, G. B., Stauffer, S., Sullivan, T., Cleveland, L., Southon, E., Reid, S., Magidson, V., Iversen, E. S. J., & Sharan, S. K. A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays. NPJ Genomic Medicine, 5(1), 52. (2020). https://doi.org/10.1038/s41525-020-00158-5

Anderson, M. J., Magidson, V., Kageyama, R., & Lewandoski, M. Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function. ELife, 9. (2020). https://doi.org/10.7554/eLife.55608

Chrisafis, G., Wang, T., Moissoglu, K., Gasparski, A. N., Ng, Y., Weigert, R., Lockett, S. J., & Mili, S. Collective cancer cell invasion requires RNA accumulation at the invasive front. Proceedings of the National Academy of Sciences of the United States of America, 117(44), 27423–27434. (2020). https://doi.org/10.1073/pnas.2010872117

Philippou, Y., Sjoberg, H. T., Murphy, E., Alyacoubi, S., Jones, K. I., Gordon-Weeks, A. N., Phyu, S., Parkes, E. E., Gillies McKenna, W., Lamb, A. D., Gileadi, U., Cerundolo, V., Scheiblin, D. A., Lockett, S. J., Wink, D. A., Mills, I. G., Hamdy, F. C., Muschel, R. J., & Bryant, R. J. Impacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model. British Journal of Cancer, 123(7), 1089–1100. (2020). https://doi.org/10.1038/s41416-020-0956-x

Leng, Y., Sim, S., Magidson, V., & Wolin, S. L. Noncoding Y RNAs regulate the levels, subcellular distribution and protein interactions of their Ro60 autoantigen partner. Nucleic Acids Research, 48(12), 6919–6930. (2020). https://doi.org/10.1093/nar/gkaa414

Somasundaram, V., Gilmore, A.C., Basudhar, D., Palmieri, E.M., Scheiblin, D.A., Heinz, W.F., Cheng, R.Y.S., Ridnour, L.A., Altan-Bonnet, G., Lockett, S.J., McVicar, D.W. & Wink, D.A. Inducible nitric oxide synthase-derived extracellular nitric oxide flux regulates proinflammatory responses at the single cell level. Redox Biology 28, 101354 (2020). https://doi.org/10.1016/j.redox.2019.101354

Zakrevsky P, Kasprzak WK, Heinz WF, Wu W, Khant H, Bindewald E, et al. Truncated Tetrahedral RNA Nanostructures Exhibit Enhanced Features for Delivery of RNAi Substrates. Nanoscale 12(4) 2555–2568 (2020).  https://doi.org/10.1039/c9nr08197f

Sun, Z., Cagliero, C., Izard, J., Chen, Y., Zhou, Y.N., Heinz, W. F., Schneider, T.D. & Jin, D.J. Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli Nucleic Acids Research 47, 3970-3985 (2019). https://doi.org/10.1093/nar/gkz159

Sahabandu, N., Kong, D., Magidson, V., Nanjundappa, R., Sullenberger, C., Mahjoub, M.R. & Loncarek, J. Expansion microscopy for the analysis of centrioles and cilia. J Microsc 276, 145-159 (2019).  https://doi.org/10.1111/jmi.12841

Nunn, N., Prabhakar, N., Reineck, P., Magidson, V., Kamiya, E., Heinz, W.F., Torelli, M.D., Rosenholm, J., Zaitsev, A. & Shenderova, O. Brilliant blue, green, yellow, and red fluorescent diamond particles: synthesis, characterization, and multiplex imaging demonstrations. Nanoscale (2019). https://doi.org/10.1039/c9nr02593f

Matarlo, J.S., Krumpe, L.R.H., Heinz, W.F., Oh, D., Shenoy, S.R., Thomas, C.L., Goncharova, E.I., Lockett, S.J. & O’Keefe, B.R. The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation. Cell Chemical Biology, 1-10 (2019).  https://doi.org/10.1016/j.chembiol.2019.04.011 

Kulkarni, R.A., Briney, C.A., Crooks, D.R., Bergholtz, S.E., Mushti, C., Lockett, S.J., Lane, A.N., Fan, T.W., Swenson, R.E., Marston Linehan, W. & Meier, J.L. Photoinducible Oncometabolite Detection. Chembiochem 20, 360-365 (2019.  https://doi.org/10.1002/cbic.201800651

Insinna, C., Lu, Q., Teixeira, I., Harned, A., Semler, E.M., Stauffer, J., Magidson, V., Tiwari, A., Kenworthy, A.K., Narayan, K. & Westlake, C.J. Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. Nat Commun 10, 428 (2019). https://doi.org/10.1038/s41467-018-08192-9

Fernandez, M.V., Delviks-Frankenberry, K.A., Scheiblin, D.A., Happel, C., Pathak, V.K. & Freed, E.O. Authentication Analysis of MT-4 Cells Distributed by the National Institutes of Health AIDS Reagent Program. Journal of Virology 93 (2019).  https://doi.org/10.1128/jvi.01390-19 

Basudhar, D., Bharadwaj, G., Somasundaram, V., Cheng, R.Y.S., Ridnour, L.A., Fujita, M., Lockett, S.J., Anderson, S.K., McVicar, D.W. & Wink, D.A. Understanding the tumour micro-environment communication network from an NOS2/COX2 perspective. Br J Pharmacol 176, 155-176 (2019). https://doi.org/10.1111/bph.14488

Singh, S.K., Singh, S., Gadomski, S., Sun, L., Pfannenstein, A., Magidson, V., Chen, X., Kozlov, S., Tessarollo, L., Klarmann, K.D. & Keller, J.R. Id1 Ablation Protects Hematopoietic Stem Cells from Stress-Induced Exhaustion and Aging. Cell Stem Cell 23, 252-265.e258 (2018). https://doi.org/10.1016/j.stem.2018.06.001

Liu, J., Kline, B.A., Kenny, T.A., Smith, D.R., Soloveva, V., Beitzel, B., Pang, S., Lockett, S., Hess, H.F., Palacios, G., Kuhn, J.H., Sun, M.G. & Zeng, X.K. A novel sheet-like virus particle array is a hallmark of Zika virus infection. Emerging Microbes & Infections 7 (2018).  https://doi.org/10.1038/s41426-018-0071-8

Kunduri, G., Turner-Evans, D., Konya, Y., Izumi, Y., Nagashima, K., Lockett, S., Holthuis, J., Bamba, T., Acharya, U. & Acharya, J.K. Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants. Proceedings of the National Academy of Sciences of the United States of America 115, E8919-E8928 (2018).  https://doi.org/10.1073/pnas.1808463115

Michie, M.S., Gotz, R., Franke, C., Bowler, M., Kumari, N., Magidson, V., Levitus, M., Loncarek, J., Sauer, M. & Schnermann, M.J. Cyanine Conformational Restraint in the Far-Red Range. Journal of the American Chemical Society 139, 12406-12409 (2017). https://doi.org/10.1021/jacs.7b07272

Yiran Li, Stephen J. Lockett, Robert J. Kinders, Wojciech Czaja: Detection of epithelial versus mesenchymal regions in 2D images of tumor biopsies using shearlets. https://doi.org/10.1109/ISBI.2018.8363720

Insinna-Kettenhofen, C., Lu, Q., Teixeira, I., Harned, A.S., Semler, E., Stauffer, J., Magidson, V., Narayan, K. & Westlake, C. Exploring PACSIN membrane tubulation regulation during intracellular ciliogenesis using 3D electron microscopy.  https://doi.org/10.1038/s41467-018-08192-9.

Chua, J., Senft, J.L., Lockett, S.J., Brett, P.J., Burtnick, M.N., DeShazer, D. & Friedlander, A.M. pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells. Infection and Immunity 85 (2017).https://doi.org/10.1128/iai.00586-16 

Basudhar, D., Glynn, S.A., Greer, M., Somasundaram, V., No, J.H., Scheiblin, D.A., Garrido, P., Heinz, W.F., Ryan, A.E., Weiss, J.M., Cheng, R.Y.S., Ridnour, L.A., Lockett, S.J., McVicar, D.W., Ambs, S. & Wink, D.A. Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer. Proceedings of the National Academy of Sciences 114, 13030-13035 (2017). https://doi.org/10.1073/pnas.1709119114

Thirthagiri, E., Klarmann, K.D., Shukla, A.K., Southon, E., Biswas, K., Martin, B.K., North, S.L., Magidson, V., Burkett, S., Haines, D.C., Noer, K., Matthai, R., Tessarollo, L., Loncarek, J., Keller, J.R. & Sharan, S.K. BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation. Human Molecular Genetics 25, 1934-1945 (2016).https://doi.org/10.1093/hmg/ddw066 

Nandy, K., Chellappa, R., Kumar, A. & Lockett, S.J. Segmentation of Nuclei from 3D Microscopy Images of Tissue via Graphcut Optimization. IEEE Journal on Selected Topics in Signal Processing 10, 140-150 (2016). https://doi.org/10.1109/JSTSP.2015.2505148 

Kuhns, D.B., Fink, D.L., Choi, U., Sweeney, C., Lau, K., Priel, D.L., Riva, D., Mendez, L., Uzel, G., Freeman, A.F., Olivier, K.N., Anderson, V.L., Currens, R., Mackley, V., Kang, A., Al-Adeli, M., Mace, E., Orange, J.S., Kang, E., Lockett, S.J., Chen, D., Steinbach, P.J., Hsu, A.P., Zarember, K.A., Malech, H.L., Gallin, J.I. & Holland, S.M. Cytoskeletal abnormalities and neutrophil dysfunction in WDR1 deficiency. Blood 128, 2135-2143 (2016).https://doi.org/10.1182/blood-2016-03-706028 

Jiang, H., Promchan, K., Lin, B.R., Lockett, S., Chen, D., Marshall, H., Badralmaa, Y. & Natarajan, V. LZTFL1 Upregulated by All-Trans Retinoic Acid during CD4(+) T Cell Activation Enhances IL-5 Production. Journal of Immunology 196, 1081-1090 (2016). https://doi.org/10.4049/jimmunol.1500719