Staff Biographies-David Scheiblin Ph.D.

NCI Optical Microscopy Laboratory

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David Scheiblin, Ph.D.

Scientist

Optical Microscopy and Analysis Laboratory

Background

David Scheiblin received his Ph.D. in 2014 in the Department of Biological Sciences at the University of Delaware, USA. He has 11 years of experience in the microscopy field working in biotechnology industry, government research, academic research, and non-profit research institutes. He has worked in three different multi-user bioimaging facilities. His research interests include the development of new optical microscopy techniques for cancer biology. Currently, his research includes the development of Multiplex Immunofluorescent techniques to look at targeted biological pathways of interest to study the tumor microenvironment. He has published or been acknowledged on over 10 peer reviewed papers and over 45 abstracts for international, national, and local conferences in his short career. He has also been awarded multiple grants and honors.

Selected Publications

Coexpression of NOS2 and COX2 accelerates tumor growth and reduces survival in estrogen receptor-negative breast cancer.  Basudhar D, Glynn SA, Greer M, Somasundaram V, No JH, Scheiblin DA, Garrido P, Heinz WF, Ryan AE, Weiss JM, Cheng RYS, Ridnour LA, Lockett SJ, McVicar DW, Ambs S, Wink DA.  Proc Natl Acad Sci U S A. 2017 Dec 5;114(49):13030-13035. 

The molecular mechanisms underlying lens fiber elongation.   Audette DS, Scheiblin DA, Duncan MK. . Exp Eye Res. 2017 Mar;156:41-49. 

Beta-1 integrin is important for the structural maintenance and homeostasis of differentiating fiber cells.  Scheiblin DA, Gao J, Caplan JL, Simirskii VN, Czymmek KJ, Mathias RT, Duncan MK.Int J Biochem Cell Biol. 2014 May;50:132-45.